³ô¼°²ñ¼Ò¥¸¡¼¥ó¥±¥¢¸¦µæ½ê
¥Û¡¼¥à English
¥×¥í¥Õ¥£¡¼¥ë
²ñ¼Ò¾ðÊó
²ñ¼Ò±è³×
¼ÒĹ°§»¢
»ö¶ÈÆâÍÆ
¸¦µæ³«È¯
¥Ë¥å¡¼¥¹
¥Ë¥å¡¼¥¹¥ê¥ê¡¼¥¹
¥È¥Ô¥Ã¥¯¥¹
¥ê¥¯¥ë¡¼¥È
¤ªÌ䤤¹ç¤ï¤»
Publication List

 2005ǯ¡¡¡¡¡¡2006ǯ¡¡¡¡¡¡2007ǯ¡¡¡¡¡¡2008ǯ¡¡¡¡¡¡2009ǯ

 2010ǯ¡¡¡¡¡¡2011ǯ¡¡¡¡¡¡2012ǯ¡¡¡¡¡¡2013ǯ¡¡¡¡¡¡2014ǯ

 2015ǯ¡¡¡¡¡¡2016ǯ¡¡¡¡¡¡2017ǯ

 

2017ǯ

¡ÊÏÀʸ¡Ë

Furuichi Y.

Caps on Eukaryotic mRNAs¡§An update since 2014 In: eLS.¡¡John Wiley & Sons, Ltd. Chichester. in pess (2017)

¡Ê³Ø²ñȯɽ¤Ê¤É¡Ë

¸Å»ÔÂÙ¹¨

¡Ö¡ÊÆÃÊֱ̹é¡Ë¥­¥ã¥Ã¥×¹½Â¤m7GpppNm¤Îȯ¸«¤Ë¤è¤ëmRNA¸¦µæ¤Î¿ÊŸ¡×¡¡Âè19²óRNA³Ø²ñǯ²ñ, ÉÙ»³

Nakamoto K, Akao Y, Furuichi Y, Ueno Y.

¡ÖDesin and synthesis of cRGD-siRNA conjugates¡× ¡¡ÆüËܳ˻À°åÌô³Ø²ñ, 2017, »¥ËÚ

 

2016ǯ

 

2015ǯ

¡ÊÏÀʸ¡Ë

Mizutani T, Ishizaka A, Furuichi Y.

The Werner Protein Acts as a Coactivator of Nuclear Factor ¦Ê B¡ÊNK- ¦Ê B) on HIV-1 and Interleukin-8 (IL-8) Promoters.J Biol Chem. 290, 18391-9 (2015)

Takemoto M, Yamaga M, Furuichi Y, Yokote K.

Astaxanthin Improves Nonalcoholic Fatty Liver Disease in Werner Syndrome with Diabetes Mellitus. J. Am. Geriatr.soc. 63, 1271-3 (2015)

Furuichi Y.

Discovery of m7G-cap in eukaryotic mRNAs (Review) Proc. Jpn. Acad. Ser. B 91, 394-408 (2015)

Uchiumi F, Seki M, Furuichi Y.

Helicases and human diseases. Front Genet. 39. (2015) doi:10.3389/fgene.

Futami K, Furuichi Y.

RECQL1 and WRN DNA repair helicases: Potential therapeutic targets and proliferative makers against cancers. Fronties in genetics. (2015) doi:10.3389/fgene

 

¡Ê³Ø²ñȯɽ¤Ê¤É¡Ë

ÃÝËÜÌ­¡¢»³²ìÀµÌï¡¢¸Å»ÔÂÙ¹¨¡¢²£¼ê¹¬ÂÀϺ

¥¢¥¹¥¿¥­¥µ¥ó¥Á¥ó¤Ë¤è¤ë¥¦¥¨¥ë¥Ê¡¼¾É¸õ·²´µ¼Ô¤ÎNAFLD¡ÊÈ󥢥륳¡¼¥ëÀ­»éËÃÀ­´Î¼À´µ¡Ë¤Î²þÁ±¡¤Âè11²ó¥¢¥¹¥¿¥­¥µ¥ó¥Á¥ó¸¦µæ²ñ¡¤2015¡¤µþÅÔ

¸Å»ÔÂÙ¹¨

À÷¿§ÂΰÂÄê²½¤Ë´Ø¤¹¤ë°äÅÁ»Ò¤òɸŪ¤È¤¹¤ë´âºÙ˦ÆðÛŪ¥¢¥Ý¥È¡¼¥·¥¹Í¶Æ³siRNA°åÌô¤Î³«È¯¡¤Âè1²óÆüËܳ˻À°åÌô³Ø²ñ¡¤2015¡¤µþÅÔ

 

2014ǯ

¡ÊÏÀʸ¡Ë

Furuichi Y.

Caps on Eukaryotic mRNAs. In: eLs. John Wiley & Sons, Ltd. Chichester. DOI: 10.1002/9780470015902.a0000891.pub3 (2014)

Sugimoto¡¡M.

A cascade leadomg tp premature aging phenotypes including abnormal tumor profiles in Werner syndrome. Int L Mol Med. 2014 Feb; 33(2): 247-53.

¡Ê½ñÀÒ¡Ë

¿ùËÜÀµ¿®¡¢¸Å»ÔÂÙ¹¨

¡Ö·ò¹¯¼÷Ì¿¤ò¿­¤Ð¤¹¡ª¡¡¥¢¥ó¥Á¥¨¥¤¥¸¥ó¥°¤Ø¤Î¼è¤êÁȤߡסÊÅìÍνÐÈÇ¡Ë

 

2013ǯ

¡ÊÏÀʸ¡Ë

Goto M, Ishikawa Y, Sugimoto M, Furuichi Y.

Werner syndrome: a changing pattern of clinical manifestations in Japan (1917¡Á2008).

Biosci Trends. 7, 13-22. 2013.

Sanada S, Futami K, Terada A, Yonemoto K, Ogasawara S, Akiba J, Yasumoto M, Sumi A, Ushijima K, Kamura T, Furuichi Y, Yano H.

RECQL1 DNA Repair Helicase: A Potential Therapeutic Target and Proliferative Marker against Ovarian Cancer. PLoS One. 8, e72820. 2013.

 

2012ǯ

¡ÊÏÀʸ¡Ë

Miyamoto M, Furuichi Y, Komiyama T.

The high-osmolarity glycerol- and cell wall integrity-MAP kinase pathways of Saccharomyces cerevisiase are involved in adaptation to the action of killer toxin HM-1. Yeast. 29, 475-485. 2012.

Goto M, Sugimoto K, Hayashi S, Ogino T, Sugimoto M, Furuichi Y, Matuura M, Ishikawa Y, Iwaki-Egawa S, Watanabe Y.

Aging-asspcoated inflammation in healthy Japanese individuals and patients with Werner syndrome. Exp gerontol. 47, 936-939. 2012

Kubota N, Inayoshi Y, Satoh N, Fukuda T, Iwaki K, Tomoda H, Kohara M, Kataoka K, Shimamoto A, Furuichi Y, Nomoto A, Naganuma A, Kuge S.

HSC90 is required for nascent hepatitis C virus cotr protein stability in yeast cells. FEBS Lett. 586, 2318-2325. 2012.

Ds S, Kumari J, Mudgal R, Modi P, Gupta S, Futami K, Goto H, Lindor NM, Furuichi Y, Mohanty D, Sengupta S.

RECQL4 is essential for the transport of p53 to mitochondria in normal human cell in the absence of exogenous stress. J Cell Sci. 125, 2509.-2522. 2012.

Takeda-Watanabe A, Yokote K, Takemoto M, Hujimoto M, Irisuna H, Honjo S, Futami K, Furuichi Y, Saito Y.

A case of Werner syndrome without metabolic abnormality: implications for the early pathophysiology. Geriatr Gerontol Int. 12, 140-146. 2012.

 

2011ǯ

¡ÊÏÀʸ¡Ë

Kabir ME, Karim N, Krishnaswamy S, Selvakumar D, Miyamoto M, Furuichi Y, Komiyama T.

Peptide derived from fungicide HM-1 Killer toxin peptide. Appl Microbiol Biotechnol. 92, 1151-1160. 2011.

Rahman MM, Kabir ME, Krishnaswamy S, Miyamoto M, Furuichi Y, Komiyama T.

New avenues for phage-display library to produce a Cryptococcus-specific anti-idiotypic antibody of HM-1 killer toxin. J Mol Recognit. 24, 631-641. 2011.

Sugimoto M, Furuichi Y, Ide T, Goto M.

Involvement of WRN helicase in immortalization and tumorigenesis by the telomeric crisis pathway (Review). Oncol Lett. 2, 609-611. 2011.

Kabir ME, Krishnaswamy S Miyamoto M, Furuichi Y, Komiyama T.

An altered camelid-like single domain anti-idiotypic antibody fragment of HM-1 killer toxin: acts as an effective antifungal agent. Appl Microbiol Biotechnol. 90,553-564.,2011.

Krishnaswamy S, Kabir ME, Rahman MM, Miyamoto M, Furuichi Y, Komiyama T.

Isolation and characterization of recombinannt single chain fragment variable anti-idiotypic antibody specific to Aspergillus fumigatus membrane protein. J immunol Methods. 366, 60-68. 2011.

Arai A, Chano T, Futami K, Furuichi Y, Ikebuchi K, Inui T, Tameno H, Ochi Y, Shimada T, Hisa Y, Okabe H.

RECQL1 and WRN Proteins Are Potential Therapeitic Targets in Head and Neck Squamous Cell Carcinoma. Cancer Res. 71, 4598-4607. 2011.

¡ÊÁíÀâ¡Ë

Æó¸«Ï¿­¡¢¸Å»ÔÂÙ¹¨

RecQ¥Ø¥ê¥«¡¼¥¼¤òɸŪ¤È¤¹¤ësiRNAÁÏÌô¡¤°å³Ø¤Î¤¢¤æ¤ß¡¤538, 553-559, 2011.

 

2010ǯ

¡ÊÏÀʸ¡Ë

Kataoka K, Kono Y, Sugimoto M, Furuichi Y, Shichiri M, Tanaka Y.

Hepatocyte-protective and anti-oxident effects of rifampicin on human chronic hepatitis C and murine acute hepatocyte disorder. Exp Ther Med. 1, 1041. 2010.

Futami K, Ogasawara S, Goto H, Yano H, Furuichi Y.

RecQL1 DNA Repair helicase: A Potential tumor marker and therapeutic target against hepatocellular carcinoma. Int J Mol Med. 25, 537. 2010.

¡ÊÁíÀâ¡Ë

Æó¸«Ï¿­¡¢¸Å»ÔÂÙ¹¨

RNA¹©³Ø¤òÍѤ¤¤¿°åÌôÉʤؤÎÄ©Àï¡ÁsiRNA¤òÃæ¿´¤È¤·¤Æ¡Á¡¢°åÌôÉÊ°åÎŵ¡´ï¥ì¥®¥å¥é¥È¥ê¡¼¥µ¥¤¥¨¥ó¥¹, 41, 19-26, 2010.

 

2009ǯ

¡ÊÏÀʸ¡Ë

Kabir ME, Krishnaswarmy S, Miyamoto M, Furuichi Y, Komiyama T.

An improved phage-display panning method to produce an HM-1 killer toxin anti-idiotypic antibody. BMC Biotechnol. 9, 99. 2009.

Krishnaswamy S, Kabir ME, Miyamoto M, Furuichi Y, Komiyama T.

Cloning antifungal single chain fragment variable antibodies by phage display and competitive panning elution. Anal Biochem. 395, 16-24, 2009.

Abe T, Goda K, Futami K, Furuichi Y.

Detection of siRNA administered to cells and animals by using a fluorescence intensity distribution analysis polarization sysytem. Nucleic Acids Res. 37, e56, 2009.

Futami K, Furuichi Y.

Quantitation of full-size small interfering RNA by tailing with terminal deoxynucleotidyl transferase and reverse transcription-polynerase chain reaction analysis. Anal Biochem. Biochem. 385, 386-388, 2009.

Iso T, Futami K, Iwamoto T, Furuichi Y.

Effect of estrogenic agents 17¦Â-Estradilo(E2) and bisphenol A on the expression of RecQ DNA helicases in mammary tumor MCF-7 cells. J Health Sci. 55, 119-124, 2009.

¡ÊÁíÀâ¡Ë

¸Å»ÔÂÙ¹¨

¡Ö¡ÚÄÉÅé¡Û»°±º¶à°ìϺÀèÀ¸¤ò¼Å¤ó¤Ç¡×¡¡ÃÁÇò¼Á³Ë»À¹ÚÁÇ¡¤12·î¹æ¡¤Vol. 54, 2009.

Æó¸«Ï¿­¡¢¸Å»ÔÂÙ¹¨

¡Ö°äÅÁ»Ò°å³ØMOOK15¹æ¡ÁºÇ¿·RNA¤È¼À´µ¸¦µæ¡×¡ÁÂè3¾ÏRNA¸¦µæ¤«¤éÎ×¾²¤Ø-4¡¨¡¡RecQ¥Ø¥ê¥«¡¼¥¼¤òɸŪ¤È¤¹¤ësiRNAÁÏÌô¡¤Ãæ¼µÁ°ìÊÔ¡¤³ô¼°²ñ¼Ò¥á¥Ç¥£¥«¥ë¥É¥¥¡¤2009.

Æó¸«Ï¿­¡¢¸Å»ÔÂÙ¹¨

¡Ö¥Ð¥¤¥ª°åÌô¤Î³«È¯µ»½Ñ¤È¥·¡¼¥º¡×¡Á23¾ÏDNA¥Ø¥ê¥«¡¼¥¼¤òɸŪ¤È¤·¤¿RNAi·¿´â¼£ÎÅÌô¤Ø¤Î³«È¯¡¤»³ËܽÅÉ×ÊÔ¡¤¥·¡¼¥¨¥à¥·¡¼½ÐÈÇ¡¤222-234, 2009.

¸Å»ÔÂÙ¹¨

¡ÖsiRNA°åÌô¤Ë¤è¤ë´Î´â¤Îʬ»ÒɸŪ¼£Îšס¡´ÎÃÀ繡¤58(3): 395-402, 2009.

¡Ê³Ø²ñȯɽ¤Ê¤É¡Ë

¸Å»ÔÂÙ¹¨

¡Ö´â¼£ÎŤˤऱ¤Æ¡¢DNA½¤Éü¥Ø¥ê¥«¡¼¥¼¤òɸŪ¤È¤¹¤ësiRNAÁÏÌô¡×¡¡ºâÃÄË¡¿Í¹â¾¾µÜÈ޴⸦µæ´ð¶âÂè40²ó¹ñºÝ¥·¥ó¥Ý¥¸¥¦¥à¡¤2009¡¤Åìµþ

Ogasawara s, Akiba J, Nakashima O, Futami K, Furuichi Y, Yano H.

Expression of RecQL1 helicase in hepatocellular carcinoma, International Liver Cancer Association(ILCA) 3rd annual conference, 2009, Milan

¾®³Þ¸¶¹¬»Ò¡¢½©Íս㡢ÃæÅç¼ý¡¢¿¿Åĺé»Ò¡¢Ã«Àî·ò¡¢°Â¸µ¿¿´õ»Ò¡¢¸Å»ÔÂÙ¹¨¡¢Æó¸«Ï¿­¡¢ÌðÌîÇîµ×

´ÎºÙ˦´â¤Ë¤ª¤±¤ëRecQL1¥Ø¥ê¥«¡¼¥¼È¯¸½¤ÎÎ×¾²ÉÂÍý³ØŪ¸¡Æ¤¡¤Âè45²óÆüËܴΡ³Ø²ñÁí²ñ¡¤2009¡¤¿À¸Í

¾®³Þ¸¶¹¬»Ò¡¢½©Íս㡢ÃæÅç¼ý¡¢¿¿Åĺé»Ò¡¢¼é²°Éáµ×»Ò¡¢Ã«Àî·ò¡¢°Â¸µ¿¿´õ»Ò¡¢¸Å»ÔÂÙ¹¨¡¢Æó¸«Ï¿­¡¢ÌðÌîÇîµ×

´ÎºÙ˦´â¤Ë¤ª¤±¤ëRecQL1¥Ø¥ê¥«¡¼¥¼È¯¸½¤ÎÎ×¾²ÉÂÍý³ØŪ¸¡Æ¤¡¤ÆüËÜÉÂÍý³Ø²ñ¡¡Âè98²óÁí²ñ¡¤2009¡¤µþÅÔ

 

2008ǯ

¡ÊÏÀʸ¡Ë

Hirose K, Wakashin H, Oki M, Kagami S, Suto A, Ikeda K, Watanabe N, Iwamoto I, Furuichi Y, Nakajima H.

GS143, an IkappaB ubiquitination inhibitor, inhibits allergic airway inflammation in mice. Biochem Biophys Res Commun. 374, 507-511, 2008.

Futami K, Kumagai E, Makino H, Sato A, Takagi M, Shimamoto A, Furuichi Y.

Anticancer activity of RecQL1 helicase siRNA in mouse xenograft models. Cancer Sci. 99, 1227-1236, 2008.

Izumikawa K, Yanagida M, Hayano T, Tachikawa H, Komatsu W, Shimamoto A, Futami K, Furuichi Y, Shinkawa T, Yamauchi Y, Isobe T, Takahashi N.

Association of human DNA helicase RecQ5beta with RNA polymerase ­¶ and its possible role in transcription. Biochem J. 413, 505-516, 2008.

Futami K, Ishikawa Y, Goto M, Furuichi Y, Sugimoto M.

Role of Werner syndrome gene product helicase in carcinogenesis and in resistance to genotoxins by cancer cells. Cancer Sci. 99, 843-848, 2008.

Nakajima H, Fujiwara H, FUruichi Y, Tanaka K, Shimbara N.

A novel small-molecule inhibitor of NF-kappaB signaling. Biochem Biophys Res Commun, 368, 1007-1013, 2008.

Futami K, Kumagai E, Makino H, Goto H, Takagi M, Shimamoto A, Furuichi Y.

Induction of mitotic cell death in cancer cells by small interference RNA suppressing the expression of RecQL1 helicase. Cancer Sci. 99, 71-80, 2008.

¡ÊÁíÀâ¡Ë

Æó¸«Ï¿­¡¢¸Å»ÔÂÙ¹¨

1.¡¡¡ÖÏ·²½¤Îµ¡½ø²òÌÀ¤È¤½¤ÎÂкö¡×¡Á7.¡¡¡ÖÁáÏ·¾É¤È¤½¤Îµ¡½ø¤òÍøÍѤ·¤¿¹³´âºÞÁÏÌô¡×¡¤Surgery Frontier, Vol.15, No.4, 48(394)-54(400), 2008.

Æó¸«Ï¿­¡¢¸Å»ÔÂÙ¹¨

¡ÖRecQ¥Ø¥ê¥«¡¼¥¼·²¤Ë¤è¤ë¥²¥Î¥à°Ý»ý¤È¼À´µ¡¢¤½¤·¤ÆÁÏÌô¤Ø¤Î±þÍѡס¤ºÙ˦¹©³Ø¡¤Vol. 27, No.10,1020-1026, 2008.

Æó¸«Ï¿­¡¢¸Å»ÔÂÙ¹¨

¡Ö¤¬¤ó¤Îʬ»ÒɸŪ¼£ÎšסÁ15¾Ï¤¬¤ó¼£ÎŤظþ¤±¤¿RNAÁÏÌô¡¤ÄáÈøδÊÔ¡¤ÆƲ¡¤90-97, 2008.

 

2007ǯ

¡ÊÏÀʸ¡Ë

Futami K, Takagi M, Shimamoto A, Sugimoto M, Furuichi Y.

Increased chemotherapeutic activity of camptothecin in cancer cells by siRNA-induced silencing of WRN helicase. Bio Pharm Bull. 30, 1958-1961, 2007.

Futami K, Shimamoto A, Furuichi Y.

Mitochondrial and Nuclear Localization of human Pif1 helicase. Biol Pharm Bull. 30, 1685-1692, 2007.

Oishi M, Nagasaki Y, Nishiyama N, Itaka K, Takagi M, Shimamoto A, Furuichi Y, Kataoka K.

Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly(ethylene glycol)-siRNA conjugate formulated in REGylated polyplexes. ChemMedChem. 2, 1290-1297, 2007.

Iso T, Futami K, Iwamoto T, Furuichi Y.

Modulation of the Expression of Bloom Helicase by Estrogenic Agents. Biol Pharm Bull. 30,266-271, 2007.

¡ÊÁíÀâ¡Ë

Æó¸«Ï¿­¡¢¸Å»ÔÂÙ¹¨

¡Ö¤¬¤ó¼£ÎŤء¢siRNA°åÌô¤Ø¤Î´üÂԡץҥ塼¥Þ¥ó¥µ¥¤¥¨¥ó¥¹¡Ê²ñÊó¡Ë, Vol 18, No.6, 14-17, 2007.

¡Ê³Ø²ñȯɽ¤Ê¤É¡Ë

Æó¸«Ï¿­¡¢¹âÌÚ´ð¼ù¡¢ÅèËܸ²¡¢¿ùËÜÀµ¿®¡¢¸Å»ÔÂÙ¹¨

WRN¥Ø¥ê¥«¡¼¥¼¤Î¥µ¥¤¥ì¥ó¥·¥ó¥°¤Ë¤è¤ë´âºÙ˦¤Î¥«¥ó¥×¥È¥Æ¥·¥ó´¶¼õÀ­¸þ¾å¡¤BMB2007¡¤²£ÉÍ

 

2006ǯ

¡ÊÏÀʸ¡Ë

S£èibata S, Sasaki M, Miki T, Shimamoto A, Furuichi Y, Katahira J, Yoneda Y.

Exportin-5 orthologues are functionally divergent among species. Nucleic Acids Res. 34, 4711-4721, 2006.

Woo LL, Futami K, Shimamoto A, Furuichi Y, Frank KM.

The Rothmund-Thomson Gene, RECQL4, Localized to the nucleolus in response to oxidative stress. Exp Cell Res. 312, 3443-3457, 2006.

Selvakumar D, Karim N, Miyamoto M, Furuichi Y, Komiyama T.

Recombinant single-chain anti-idiotypic antibody: an effective fungal beta-1,3-glucan synthase inhibitor. Biol Pharm Bull. 29, 1848-1853, 2006.

Selvakumar D, Miyamoto M, Furuichi Y, Komiyama T.

Inhibition of fungal beta-1,3-glucan synthase and cell growth byHM-1 killer toxin single-chain anti-idiotypic antibodies. Antimicrob Agents Chemother. 50, 3090-3097, 2006.

Goto M, Okawa-Takatsuji M, Aotsuka S, Nakai H, Shimizu M, Goto H, Shimamoto A, Furuichi Y.

Significant elevation of IgG anti-WRN (RecQ3 RNA/DNA helicase) antibody in systemic sclerosis. Mod Rheumatol. 16, 229-234, 2006.

Kawabe Y, Seki M, Yoshimura A, Nishino K, Hayashi T, Takeuchi T, Iguchi S, Kusa Y, Ohtsuki M, Tsuyama T, Imamura O, Matsumoto T, Furuichi Y, Tada S, Enomoto T.

Analyses of the interaction of WRNIP1 with Werner syndrome protein (WRN) in vitro and in the cell, DNA Repair (Amst). 5, 816-828, 2006.

Selvakumar D, Miyamoto M, Furuichi Y, Komiyama T.

Inhibition of beta-1,3-glucan synthase and cell growth of Cryptococcus species by recombinant single-chain anti-idiotypic antibodies. J Antibiot (Tokyo). 59, 73-79, 2006.

Selvakumar D, Zhand QZ, Miyamoto M, furuichi Y, Komiyama T.

Identification and acharacterization of a neutralizing monoclonal antibody for the epitope on HM-1 killer toxin. J Biochem. 139, 399-406, 2006.

Iso T, Watanabe T, Iwamoto T, Shimamoto A, Furuichi Y.

DNA Damage caused by bisphenol A and estradiol through estrogenis activity. Biol Pharm Bull. 29, 206-210, 2006.

(ÁíÀâ¡Ë

¹âÌÚ´ð¼ù¡¢º´Æ£¤¢¤æ¤ß¡¢ÅèËܸ²¡¢¸Å»ÔÂÙ¹¨

¡Ö°äÅÁ»Ò°å³ØMOOK4¹æ¡ÁRNA¤ÈÁÏÌô¡×¡ÁRecQ¥Ø¥ê¥«¡¼¥¼¤òɸŪ¤È¤·¤¿À©´âºÞ¼£ÎÅ¡¤Ãæ¼µÁ°ìÊÔ¡¤³ô¼°²ñ¼Ò¥á¥Ç¥£¥«¥ë¥É¥¥¡¤2006.

¡Ê³Ø²ñȯɽ¤Ê¤É¡Ë

°ÂÉôδ»Ë¡¢¹çÅÄÏ»ˡ¢Æó¸«Ï¿­¡¢¸Å»ÔÂÙ¹¨

·Ö¸÷Êи÷²òÀÏË¡¤Ë¤è¤ësiRNA¤ÎÀ¸ÂÎÆâÇ»ÅÙ¬ÄêË¡¤Î³«È¯¡¤Âè17²ó¥¢¥ó¥Á¥»¥ó¥¹¥·¥ó¥Ý¥¸¥¦¥à¡¤2006, ¶âÂô

Æó¸«Ï¿­¡¢·§Ã«±ÉÈþ¡¢ËÒÌî¹°¡¢°ËÆ£À鳨¡¢¸Å»Ô¹¯¹°

RecQL1-siRNA¤Ë¤è¤ë¹³´âºÞ³«È¯¡¤Âè17²ó¥¢¥ó¥Á¥»¥ó¥¹¥·¥ó¥Ý¥¸¥¦¥à¡¤2006, ¶âÂô

¼Åij¨Î¤»Ò¡¢Â¿Åļþ±¦¡¢Æó¸«Ï¿­¡¢¸Å»ÔÂÙ¹¨¡¢´ØÀ¯¹¬¡¢±ÝËÜÉðÈþ

RecQL1 siRNA¤Î½èÍý¤Ë¤è¤ë¤¬¤óºÙ˦»à¡¤ÆüËÜÌô³Ø²ñÅìËÌ»ÙÉô²ñ¡¡Âè45²óÂç²ñ, 2006, ÀçÂæ

¾®Ìî°¦Èþ¡¢¾®À¾Í³µª¡¢±ÊÅIJÂÂå»Ò¡¢¹âÉô¾Í»Ò¡¢¾å¿ùÀ²°ì¡¢»°¹¥Ã£Ìé¡¢²Ï¹çʸͺ¡¢Æó¸«Ï¿­¡¢ÅèËܸ²¡¢ÊÒÊ¿Àµ¿Í¡¢hnRNP A1/hnRNP D0 ¥¿¥ó¥Ñ¥¯¼Á¤È¥Æ¥í¥á¥¢Ä¹¤Î´Ø·¸¡¢ÆüËÜʬ»ÒÀ¸Êª³Ø²ñ2006¥Õ¥©¡¼¥é¥à¡¢2006, ̾¸Å²°

 

2005ǯ

¡ÊÏÀʸ¡Ë

Sawada K, Noda K, Nakajima H, Shimbara N, Furuichi Y, Sugimoto M.

Differential cytotoxicity of anticancer agents in pre- and post-immortal lymphoblastoid cell lines. Biol Pharm Bull. 28, 1202-1207, 2005.

Miyamoto M, Han GD, Kimura T, Furuichi Y, Komiyama T.

Alanine-scanning mutagenesis of HM-1 killer toxin and the essential residues for killing activity/ J Biochem. 137, 517-22. 2005.

Takahashi M, Okada J, Ito K, Hashimoto M, Hashimoto K, Yoshida Y, Furuichi Y, Ohta Y, Mishiro S, Gemma N.

Construction of an electrochemical DNA chip for simultaneous genotyping of single nucleotide polymorphisms. Analyst. 130, 687-93. 2005.

Sengupta S, Shimamoto A, Koshiji M, Pedeux R, Rusin M, Spillare EA, Shen JC, Huang LE, Lindor NM, Furuichi Y, Harris CC.

Tumor suppressor p53 represses transcription of RECQ4 helicase. Oncogene 24, 1738-48, 2005.

Futami K, Goto H, Shimamoto A, Watanabe T, Furuichi Y.

Quantitative analysis of Werner helicase activity be using the single-molecule florescence detection sistem MF10S. Biol Pham Bull. 28, 9-12, 2005.

¡ÊÁíÀâ¡Ë

ÅèËܸ²¡¢Æó¸«Ï¿­¡¢¸Å»ÔÂÙ¹¨

¡Ö¥²¥Î¥à¤Î°ÂÄê²½µ¡¹½¡½Ï·²½¸¦µæ¤«¤é´â¼£ÎŤؤαþÍѡס¤Biotherapy 19, 390-397, 2005.

¿ùËÜÀµ¿®¡¢°æ½ÐÍø·û¡¢¸Å»ÔÂÙ¹¨

¡ÖEBV¤Ë¤è¤ëBºÙ˦¤ÎÉԻಽ¡¦´â²½¡½¡½ÄêÀâ¤ÎÈÝÄê¡×¡¤ÃÁÇò¼Á³Ë»À¹ÚÁÇ,3·î¹æ¡¤Vol, 50, 283-288, 2005.

 

Copyright GeneCare Research Institute Co.,Ltd. All rights reserved. ¥Ú¡¼¥¸¤Î¥È¥Ã¥×